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KMID : 1144820220280040307
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대한의생명과학회지
2022 Volume.28 No. 4 p.307 ~ p.311
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Protective Effect of Aqueous Extract from Erigeron annuus Against Cell Death Induced by Free Radicals
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Jeong Myeong-guk
Kwon Hyeok-jin
Ju Young-don
Choi Go-Eun
Hyun Kyung-Yae
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Abstract
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The extract of EA lacks studies showing its efficacy other than that it contains caffeic acid, an active compound that has antioxidant and neuroprotective effects on nerve cells. Therefore, in this study, we attempted to determine the effectiveness of EA extraction. In this study, we performed a DPPH assay to determine the antioxidant potential of EA. And then, the cytotoxic concentration of EA in HaCaT keratinocytes was determined, and the antioxidant effect was determined by measuring the malondialdehyde (MDA). The results of DPPH, a chemical antioxidant assay, clearly demonstrated the antioxidant capacity of EA extracted with distilled water. In addition, cell-based assays provide useful information on the protective effect of EA on oxidative stress-induced apoptosis.
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KEYWORD
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Erigeron annuus, Protective effect, 2,2-diphenyl-1-picrylhydrazyl (DPPH), Malondialdehyde (MDA), Free radicals
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